I'm looking for a list of contrast agents for comparison purposes related to osmolarity. Which are greater risk of tissue necrosis after extravasation? There was a link on this site but it doesn't work.
That information is contained in each of the package inserts or manufacturer directions for use for each drug. I have not ever found a list already compiled. I am giving videoconference presentations sponsored by BD and have some of this information in that handout. Osmolarity varies by concentration of the contrast. All but 2 or hypertonic or hyperosmolar. I have never seen any studies reporting that one agent is more or less likely to cause tissue necrosis. The risk is related to the quantity of agent that enters the SC tissue and how quickly it is recognized. I am afraid you will need to compile this information for your project. Lynn
There is a list on this site under "Power Injectible Midlines" submitted by SaHariis on Wed May 9 2012. If the copy/paste function worked I would paste it here for you.
I note the original question was for osmolarity of contrast agents. The table says osmolality. Could you clarify that the table is osmolality (or osmolarity)? Thanks.
That information is contained in each of the package inserts or manufacturer directions for use for each drug. I have not ever found a list already compiled. I am giving videoconference presentations sponsored by BD and have some of this information in that handout. Osmolarity varies by concentration of the contrast. All but 2 or hypertonic or hyperosmolar. I have never seen any studies reporting that one agent is more or less likely to cause tissue necrosis. The risk is related to the quantity of agent that enters the SC tissue and how quickly it is recognized. I am afraid you will need to compile this information for your project. Lynn
Lynn Hadaway, M.Ed., RN, BC, CRNI
Lynn Hadaway Associates, Inc.
126 Main Street, PO Box 10
Milner, GA 30257
Website http://www.hadawayassociates.com
Office Phone 770-358-7861
There is a list on this site under "Power Injectible Midlines" submitted by SaHariis on Wed May 9 2012. If the copy/paste function worked I would paste it here for you.
edit: figured it out! see above
Agent Osmolality
Isovue®-200 (Bracco) Iopamidol Nonionic Low...413
Isovue®-250 (Bracco) Iopamidol Nonionic Low...524
Isovue®-300 (Bracco) Iopamidol Nonionic Low...616
Isovue®-370 (Bracco) Iopamidol Nonionic Low...796
Omnipaque™ 140 Iohexol Nonionic Low.............322
Omnipaque® 180 Iohexol Nonionic Low.............408
Omnipaque™ 240 Iohexol Nonionic Low.............520
Omnipaque™ 300 Iohexol Nonionic Low.............672
Omnipaque™ 350 Iohexol Nonionic Low.............844
Optiray® 160 Ioversol Nonionic Low..................355
Optiray®240 Ioversol Nonionic Low...................502
Optiray® 300 Ioversol Nonionic Low..................651
Optiray® 320 Ioversol Nonionic Low..................702
Optiray® 350 Ioversol Nonionic Low..................792
Oxilan® 300 (Guerbet) Ioxilan Nonionic Low......585
Oxilan® 350 (Guerbet) Ioxilan Nonionic Low......695
Ultravist® 150 Iopromide Nonionic Low.............328
Ultravist® 240 Iopromide Nonionic Low.............483
Ultravist® 300 Iopromide Nonionic Low............ 607
Ultravist® 370 Iopromide Nonionic Low............ 774
Visipaque-320™ Iodixanol Nonionic Low............290
Jill,
Thank you. We are looking at various vendors and contract renewal; this information is helpful.
I note the original question was for osmolarity of contrast agents. The table says osmolality. Could you clarify that the table is osmolality (or osmolarity)? Thanks.
One is per kg and one is per mL, but there is virtually no difference in the actual numbers. Lynn
Lynn Hadaway, M.Ed., RN, BC, CRNI
Lynn Hadaway Associates, Inc.
126 Main Street, PO Box 10
Milner, GA 30257
Website http://www.hadawayassociates.com
Office Phone 770-358-7861