Wonder if anyone ever use sodium bicarb instead of alteplase to unblock fibrin clot from a central line catheter? Our doctor recommended this practice. Appreciate any advice.
Bicarbonate is only indicated to reverse occlusion from some drug precipitate. It will not lyse thrombus or fibrin. When the drug has an alkaline or high pH, the precipitate occurs because the pH drops. To reverse this bicarbonate is instilled. When the precipitated drug has a low pH instill hydrochloric acid to reverse the precipitate. When occlusion is caused by fibrin of thrombus only a Thrombolytic dru will work. To make the appropriate choice, you must do an assessment of events leading up to occlusion lynn
Bicarbonate is only indicated to reverse occlusion from some drug precipitate. It will not lyse thrombus or fibrin. When the drug has an alkaline or high pH, the precipitate occurs because the pH drops. To reverse this bicarbonate is instilled. When the precipitated drug has a low pH instill hydrochloric acid to reverse the precipitate. When occlusion is caused by fibrin of thrombus only a Thrombolytic dru will work. To make the appropriate choice, you must do an assessment of events leading up to occlusion lynn
Lynn Hadaway, M.Ed., RN, BC, CRNI
Lynn Hadaway Associates, Inc.
126 Main Street, PO Box 10
Milner, GA 30257
Website http://www.hadawayassociates.com
Office Phone 770-358-7861