Does anyone know of any clinical studies showing the efficacy of using Pervantics(TM) swab, ( 3.15 % Chlorhexidine gluconate with 70% alcohol) is more effective than 70% alcohol swab in disinfecting needleless connectors/injection ports? Thank you.
Does anyone know of any clinical studies showing the efficacy of using Pervantics(TM) swab, ( 3.15 % Chlorhexidine gluconate with 70% alcohol) is more effective than 70% alcohol swab in disinfecting needleless connectors/injection ports? Thank you.
Dont have a PDF...but look up the classic Wendy Kaler study.
I have an electronic copy of Wendy's study I can email you if you would like! Valorie
Valorie Dunn,BSN, RN, CRNI, PLNC
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Sorry to disagree with Mark, but I would not consider the study by Wendy Kaler to be a classic study. The author has voiced some concern and states there were changes she would like to have made. There is a better more recent study on this issue conducted by the CDC. Here is the reference information and abstract
1. Mazher MA, Kallen A, Edwards JR, Donlan RM. An In Vitro evaluation of disinfection protocols used for needleless connectors of central venous catheters. Lett Appl Microbiol. 2013.
Significance and Impact of the Study: A sensitive and repeatable protocol was developed to evaluate antiseptics for disinfecting catheter needleless connectors (NCs). Povidone-iodine (PI) and chlorhexidine gluconate plus isopropanol (CGI) were more effective than isopropanol (IPA) for reducing Staphylococcus epidermidis contamination of NCs. The effectiveness of PI and CGI was reduced on NCs pre-exposed to with Klebsiella pneumoniae.
As you can see, CHG w/alcohol and povidone iodine is less effective when exposed to human serum, which would be the case in virtually all NCs. I would still prefer to rely upon the use of a disinfecting cap as opposed to manual scrubbing with the wide variety of human factors that impact the outcome of any manual procedure. Lynn
Lynn Hadaway, M.Ed., RN, BC, CRNI
Lynn Hadaway Associates, Inc.
126 Main Street, PO Box 10
Milner, GA 30257
Website http://www.hadawayassociates.com
Office Phone 770-358-7861
Thanks Lynn for the update!