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Robbin George
Decloting Agents
If a Central Line occlusion is known to be caused by a drug percipitate what is the best safest and most efficient way to resolve the problem--Are there specific antidotes for specific percipitates and if so what refernece source can be used to write policy--I have exchanged PICC in the past to resolve this problem but others want to know if this is Best Practice--Thank you in advance of your responses 
lynncrni
For drugs with a alkaline
For drugs with a alkaline pH, use sodium bicarbonate. For drugs with an acidic pH, use hydrocloric acid. There are many articles about this. Lynn

Lynn Hadaway, M.Ed., RN, BC, CRNI

Lynn Hadaway Associates, Inc.

126 Main Street, PO Box 10

Milner, GA 30257

Website http://www.hadawayassociates.com

Office Phone 770-358-7861

Robbin George
I have searched the internet
I have searched the internet looking for articles with NO result--Firstly are others using such chemical interventions and if so could you post your guidelines policy and procedure for their administration--Seems like a complicated situation for a staff nurse to deal with and one that would require a specific set of competencies 

Robbin George RN VA-BC

lynncrni
Here are a few: 1.   

Here are a few:

1.    Duffy LF, Kerzner B, Gebus V, Dice J. Treatment of central venous catheter occlusions with hydrochloric acid. Journal of Pediatrics. 1989;114(6):1002-1004.
2.    Pennington CR, Pithie AD. Ethanol lock in the management of catheter occlusion. Journal of Parenteral and Enteral Nutrition. 1987;11(5):507-508.
3.    Werlin SL, Lausten T, Jessen S, et al. Treatment of central venous catheter occlusions with ethanol and hydrochloric acid. Journal of Parenteral and Enteral Nutrition. 1994;19(5):416-418.
 

Lynn Hadaway, M.Ed., RN, BC, CRNI

Lynn Hadaway Associates, Inc.

126 Main Street, PO Box 10

Milner, GA 30257

Website http://www.hadawayassociates.com

Office Phone 770-358-7861

Gwen Irwin
You might the ONS Vascular

You might the ONS Vascular Access Guidelines for a table that has what agent to use to declot precipitants.  I don't have the most current version, but have seen in the previous 2 versions.

Gwen Irwin

Austin, Texas

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